Isolation, Structural Features, and Biological Propertiesĭiarylheptanoids have been typically isolated from the (inner) stem and the root bark of parent trees and shrubs, from the rhizomes of herbs, and also from the extracts of leaves and twigs of terrestrial plants. The present paper has, therefore, covered the recent progress in macrocyclic diarylheptanoids with a focus on their isolation, structural features, biological properties, and synthesis.Ģ. paid attention to the total synthesis of three categories of diarylheptanoids no additional summaries have been made since then. Reviews by Keserü and Nógrádi and by Zhu et al. Furthermore, the main themes of the reviews focused on the isolation, structure elucidation, and biological properties while attention to synthesis was somewhat out of scope. In addition, additional reviews and papers covering linear diarylheptanoids have appeared recently, but reviews addressing cyclic diarylheptanoids are very limited. covered the general aspects of diarylheptanoids, the reviews by Lv and She focused on their structures, distributions, biological activities and 13C-nuclear magnetic resonance (NMR) spectral data of over 400 diarylheptanoids. Although the two reviews by Claeson et al. , and by Lv and She, which included all of these three subcategories. The earlier studies on diarylheptanoids were summarized by Claeson et al. Their unique and characteristic structural features and wide range of biological properties have contributed to their popularity, which has led to continual isolation, evaluation of biological properties, and total synthesis. The present paper has, therefore, covered recent progress in cyclic diarylheptanoids focusing on the isolation, structural and biological features, and chemical synthesis. Only a few have covered cyclic diarylheptanoids and their chemical synthesis has been covered lastly by Zhu et al. Earlier studies on these diarylheptanoids have been summarized on several occasions, of which the main themes only focus on isolation, structure elucidation, and the biological properties of linear types. Since the isolation of curcumin from the rhizomes of turmeric ( Curcuma longa) in 1815 which was named curcumin, a variety of diarylheptanoids have been isolated from a number of plant families such as Aceraceae, Actinidiaceae, Betulaceae, Burseraceae, Casuarinaceae, Juglandaceae, Leguminosae, Myricaceae, and Zingiberaceae. They can be subdivided into acyclic and cyclic diarylheptanoids where the latter are further divided into meta, meta-bridged biphenyls (metacyclophanes) and meta, para-bridged diphenyl ether heptanoids (oxametapara-cyclophanes).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |